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Dominique Gagnon

Dominique Gagnon

Assistant Professor

School of Kinesiology and Health Sciences


Following my graduation from Laurentian University in Outdoor Adventure Leadership in 2005, I went to the University of Manitoba in the Laboratory of Environmental Medicine and subsequently to Finland, at the University of Jyväskylä in the Department of Biology of Physical Activity, to study the effects of environmental stress on the human body during rest and exercise.  My current research at Laurentian aims at examining how thermal changes influence oxygen availability and extraction, metabolism, and mitochdonrial signalling in muscles during exercise.  My research is closely tied to my teaching in the School of Kinesiology and Health Sciences with Exercise Physiology PHED 3126 and Environmental Physiology PHED 3051. 

I currently accept students at the Masters and PhD level.


University of Jyväskylä (Ph.D.) 2014

University of Manitoba (M.Sc.) 2009

Laurentian University (B.P.H.E.: Outdoor Adventure leadership) 2005

Academic Appointments

Senior Researcher - July 2019 to July 2021

Center for Research in Occupational Safety and Health

Assistant Professor - July 2015 to present

Laurentian University, School of Human Kinetics

Post-Doctoral Researcher - July 2014 to June 2015

University of Oulu, Institute of Biomedicine

On The Web


My main research aims at investigating the thermal influences governing oxygen delivery and extraction on skeletal muscle metabolism during exercise (NSERC funded).  I am also interested into whole-body metabolism during environmental stress and exercise.  Additional research interests include energy metabolism and bioenergetics in healthy and diseased populations, immuno-endocrine, metabolic and oxidative responses following acute and long-term strenuousphysical loading


NSERC Discovery Award (2016-2021) Thermoregulatory influences governing oxygen delivery and extraction on skeletal muscle metabolism during exercise


PHED 2507 Physiology II

PHED 3126 Exercise Physiology

PHED 4006 Fitness Evaluation and Presciption

PHED 4707 Environmental Physiology



  1. Gagnon DD, Dorman S, Ritchie S, Jagalur Mutt S, Stenbäck V, Walkowiak J, Herzig KH. (2019). Multi-day Prolonged Low- to Moderate-Intensity Exercise Exercise Mimics Training Improvements in Metabolic and Oxidative Profiles without Concurrent Chromosomal Changes in Healthy Adults. Frontiers.
  2. Stenback V, Jagalur Mutt S, Leppäluoto J, Gagnon DD, Mäkelä KA, Jokelainen J, Keinänen-Kuikaanniemi S, Herzig KH. (2019) Effect of physical activity on telomere length in elderly adults – the Oulu Cohort 1945. Frontiers 00444.
  3. Gagnon DD, Perrier L, Dorman S, Oddson B, Larivière C, Serresse O. (2019) Ambient temperature influences metabolic substrate oxidation curves and the crossover point during running and cycling in healthy men. Eur. J. Sport Sci. 1612949.
  4. Konrad J, Gagnon DD, Serresse O, Oddson B, Leduc C, Dorman S. (2019). Effect of simulated mine rescue on physiological variables and heat strain of mine rescue workers. J. Occup. Env. Med. 61(3): 251.
  5. Gagnon DD, et al. (2017) The effects of skin and core tissue cooling on deoxygenation of the vastus lateralis muscle during walking and running. J. Sports Sciences. Vol 35 (20): 1995-2004
  6. Gagnon DD, Gagnon SS, Rintamäki H, Törmäkangas T, Puukka K, Herzig KH, Kyröläinrn H (2014) The effects of cold exposure on leukocytes, hormones, and cytokines during acute exercise in humans. PLoS ONE. 9(10): e110774
  7. Mäkelä K, Gagnon DD, Leppäluoto J, Herzig KH (2014). Irisin – ‘New Kid on the Block in energy regulation’? Acta Physiol. 211(1): 5-7.
  8. Gagnon DD, Rintamäki H, Gagnon SS, Oksa J, Porvari K, Cheung SS, Herzig KH, Kyröläinen H (2014). Low-intensity shivering does not affect fuel selection during short term submaximal exercise in the cold. Appl Physiol Nutr Metab. 39: 282-291.
  9. Gagnon DD, Rintamäki H, Gagnon SS, Cheung SS, Herzig KH, Porvari K, Kyröläinen H (2013). Cold exposure enhances fat utilization but not non-esterified fatty acids, glycerol or catecholamines availability during submaximal walking and running. Front. Physiol. 10 May 2013 | doi:10.3389/fphys.2013.00099.
  10. Gagnon DD, Pretorius T, MacDonald G, Kenny GP, Giesbrecht GG (2013). Cardiovascular and ventilatory responses to dorsal, facial and whole-head water immersion in eupnea. Aviat Space Env Med. 84 (6), 573-583.
  11. Gagnon DD, MacDonald G, Pretorius T and Giesbrecht GG (2012). Clothing buoyancy affects underwater horizontal swim distance after exit from a submersed vehicle simulator. Aviat Space Env Med. 83 (11), 1077–1083.
  12. Gagnon DD, Karinen H, Pullinen T, Rintamäki H and Kyröläinen (2011). Recovery of hormonal, blood lipid and hematological profiles from a North Pole expedition. Aviat Space Env Med. 82(12), 1110-1117.
  13. Pretorius T, Gagnon DD and Giesbrecht GG (2010). Core cooling and thermal responses during whole head, face and dorsum immersion in 17°C water. J Appl Physiol; Nutr Metab. 35(5), 627-634.


1. Gagnon DD et al. (2014) Immuno-modulation of combined cold exposure and exercise on leukocyte, endocrine and cytokines responses in humans. Acta Physiol 211(Suppl 696), p 99. Abstract

2.Gagnon DD et al. (2014). Pre-exercise whole-body cooling decreases blood volume and oxygenated hemoglobin content in skeletal muscle during submaximal exercise. FASEB 28 (Suppl 1) 1106.7. Abstract

3. Gagnon DD et al. (2013). Cardiovascular and ventilatory responses to dorsal, facial and whole-head water immersion in eupnea. Appl Physiol Nutr. Metab 38 (10), p 1039. Abstract

4. Gagnon DD et al. (2013). Clothing buoyancy affects underwater horizontal swim distanceafter exit from a submersed vehicle simulator. Appl Physiol Nutr. Metab 38 (10), p 1039. Abstract

5. Gagnon DD  (2012). Acute neuro-endocrines responses during combined treadmill exercise and cold stress. Acta Physiol 206 (suppl 691), p 86. Abstract.


1. Gagnon DD (2014) The effects of Exercising in the Cold on Energy Metabolism, Skeletal Muscle Tissue Oxygenation and Immuno-Endocrine Responses. University Library of Jyväskylä, Doctoral Thesis.

2. Gagnon DD (2009). Effects of dorsal, face and whole head immersion on the dive responses in humans. University of Manitoba, Master’s Thesis.